In this case, mitochondrial membrane proteins mediate the delivery of mitochondria to autophagosomes. These proteins, collectively termed mitophagy receptors, engage the autophagy machinery via their LIR domains, which interact primarily with ATG8s.
This review aims to address these gaps by providing a comprehensive and updated synthesis of mitophagy in CVDs.
This review identifies mitophagy as a pivotal factor in the development of both cancer and NDDs, while also evaluating specific mechanisms and processes to clarify how mitophagy connects these opposing disease trajectories.
As we can see from the illustration, These Disruptions Impair Mitophagy has many fascinating aspects to explore.
These disruptions directly impair cardiomyocyte ion channel function and expression, driving the onset and progression of AF. Mitophagy, a key mechanism for mitochondrial quality control...
Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington...
