Tornatore L, Thotakura AK, Bennett J, Moretti M, Franzoso G. The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation . Trends in Cell Biology . 2012 Nov 1;22(11):557-566.
The activated nuclear factor kappa B (NF-B) pathway in VO might be a potential link in the development of AD. Likewise, the higher concentration of advanced glycation end-products in VO could be implicated in the pathogenesis of AD.
The nuclear factor kappa B (NF-B) signalling pathway is a pivotal orchestrator of inflammation, tumour progression, immune modulation, and metabolic reprogramming within the dynamic landscape of the tumour microenvironment (TME).

As we can see from the illustration, The Nuclear Factor Kappa B Signaling Pathway Integrating Metabolism has many fascinating aspects to explore.
Abstract. Nuclear factor kappa B (NF-kappa B) transcription factors are evolutionarily conserved, coordinating regulators of immune and inflammatory responses. They also play a pivotal role in oncogenesis and metabolic disorders.
Laura Tornatore; Anil K. Thotakura; Jason Bennett; Marta Moretti; Guido Franzoso. (2012). The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation. , 22(11), . doi:10.1016/j.tcb.2012.08.001. Sci-Hub .

The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation.